Compared to two clinical groups, the healthy group reported greater scores in adaptive Ratings of 54 English and 52 Swedish patients on a 65 item comprehensive psychopathology scale were used to identify the 17 most commonly occurring symptoms in primary depressive illness in the combined sample. different from bipolar depression disorder base on both CONCLUSIONS : The content of OC symptoms which is not traditionally considered a helpful factor for diagnosing a psychiatric disorder might be able to lead the clinician to the diagnosis of bipolarity in a depressed patient with OCD. In, ferent from the other items. Item-total correlations, Cronbach’s alpha (total minus item), who demonstrated that irritability is not al-. Bipolar disorders. In study 2, 200 patients diagnosed with MDD were assessed with the MADRS in face-to-face interviews. Moreover, the correlations of each of the three manic subdomains with the others and each of the three depressive subdomains with the others were consistently higher than those between manic and depressive subdomains. Akiskal and colleagues, reported that “mood swings with rapid shifts” in de-, pressed patients is the hallmark of unipolar depres-. Then all the subjects went through a semi structural clinical interview for (SCID-I) DSM-IV by one psychiatrist. The Montgomery-Asberg Depression Rating Scale (MADRS) is an expert's rating tool to assess the severity and symptoms of depression. We concluded that tDCS is an efficient therapy for patients with resistant major depression, and the benefits would remain at least for 1 month. The interviews were carried out by a trained general practitioner according to an 11-item checklist comprised of criteria C (2 items) and D (9 items) of Ghaemi et al. Can J Psychiatry. distinguish unipolar depression disorder from bipolar depression in bipolar than in unipolar affective illness: results, sessive-compulsive symptoms in patients with bipo-, of bipolar and unipolar affective comorbidity on ob-, Bipolar Spectrum Diagnostic Scale for detecting bi-, mi SN, Soleimani N. The Persian Bipolar Spectrum, Diagnostic Scale and Mood Disorder Questionnaire. Perlis RH, Fava M, Trivedi MH, Alpert J, Luther JF, Wisniewski SR, et al. a Remission: ≥1 MADRS total score at or below the cut‐off point. World Health Organization (2018). Background: The Hamilton Depression Rating Scale (HAM-D) and the Montgomery-Asberg Depression Scale (MADRS) are used worldwide and considered standard scales for evaluating depressive symptoms. This study aimed to reevaluate this subject on a different sample within a different cultural background. The groups were consisted of equal numbers of women and men. Mixed analysis of variance showed a significant difference in the mean scores for active group P = .010 and pattern of change during the study P < .001 in favor of active intervention. Also, in the bipolar group the miscellaneous compulsions (P < 0.01) were significantly more prevalent, and the washing compulsion (P < 0.001) was significantly less prevalent. young mania rating scale (YMRS). To be administered in an interview. Specificity values for most psychiatric disorders were high (>0.85); the sensitivity values were somewhat lower. The Persian translation of the SCID yields diagnoses with acceptable to good reliability and validity in a clinical population in Iran. The research sample consisted It includes items for rating mixed features, as well as being sensitive to many phenomenological elements found commonly in bipolar depression, such as hypersomnia and hyperphagia, which are not picked up by conventional depression measures. 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